Foundations
Th17 biology
Our lab helped define the Th17 lineage. We continue to map how these cells develop, how they defend mucosal barriers, and how they drive inflammation when control is lost.
Learn more →University of Alabama at Birmingham
Understanding the cells that direct immunity.
The Weaver Lab studies CD4 T cells — how they choose their fates, how they defend the body's surfaces, and how their programs are subverted in chronic inflammatory disease and cancer.
Research
Three questions, one cell type
From the discovery of the Th17 lineage to single-cell maps of the infected intestine, our work follows the CD4 T cell across health and disease.
Tissue
Mucosal & intestinal immunity
We study how effector and regulatory CD4 T cells keep the intestine in balance, and how nuclear receptors and the microbiota tune that balance.
Learn more →Disease
Dysregulation & disease
From inflammatory bowel disease to colorectal cancer and neonatal sepsis, we ask how T-cell programs go wrong and how they might be redirected.
Learn more →Selected work
Featured publications
Lab news
Latest from the lab
Join us
We're looking for curious scientists
Postdoctoral fellows, graduate students, and undergraduates who want to understand how T cells shape health and disease are welcome to get in touch.
Openings & contact